Benefits
·
Maintains
cell health
·
Promotes
normal cell cycle activity
·
Promotes
apoptosis (programmed cell death) in unhealthy cells
·
Promotes
normal nuclear factor kappa B (NF-Kappa B – protein)
and cyclooxygenase-2 (COX-2 -
enzyme) activity
·
Promotes
normal activity of the SIRT-1 gene (involved in calorie restriction, fat mobilization,
mitochondrial function)
·
Promotes
cardiovascular health (promotes normal platelet activity, helps maintain normal vasorelaxation,
provides antioxidant protection of LDL particles)
·
Superior
antioxidant and high ORAC value
·
Promotes
a healthy prostate gland
·
Helps
promote apoptosis in unhealthy prostate cells
FAQs
Who
should take this product?
Clinical
studies have shown that resveratrol extract may be helpful in promoting
apoptosis (programmed cell death) in unhealthy cells, supporting normal cell
cycle activity, promoting the normal activity of the SIRT-1 gene, thereby
supporting overall cellular health. If you are interested in promoting cellular
health and maintaining good cardiovascular health, then Isotonix Resveratrol is
perfect for you.
Do I need OPC-3 if I take this
product?
Isotonix
OPC-3 is a superior antioxidant with many health benefits. Isotonix Resveratrol
can be taken with other antioxidants; in fact, antioxidants work in several
mechanisms, and they build upon each other. For a complete comprehensive
antioxidant defense, taking OPC-3 and Resveratrol is a smart choice protecting
your body from the damaging effects of free radicals.
I
am currently taking medication to manage my cholesterol. Can I still take
Resveratrol?
There
are no documented interactions with cholesterol medication and any of the
ingredients in Resveratrol.
When
should I start to see/feel the effects of this product?What should I expect?
The
antioxidant benefits of Isotonix Resveratrol should be noticeable in about four
to six weeks. Please remember that everyone’s body is different, so for some it
may take longer to notice the benefits of Resveratrol. You should expect to
feel better and healthier overall.
Ingredients
Resveravine® (20% resveratrol extract): 10 mg
Resveratrol is a natural antioxidant found in red wine.
Resveravine is a natural extract from Vitis vinifera standardized to
contain 20% oligostilbenes. Resveravine is 100 to 300 times more concentrated
in trans-resveratrol than other products made from grape skin. It provides
antioxidant protection of low-density lipoprotein (LDL) particles, promotes
normal platelet activity, vasorelaxation and blood flow, all which support
cardiovascular health. It has been shown to promote apoptosis (programmed cell
death) in unhealthy cells. Another proposed mechanism of action involves
the study of the SIRT-1 gene (also known at the longevity gene). Sirtuins,
known as Silent Information Regulators (SIRs), are deacetylase enzymes
identified in all living creatures. Sirtuin proteins are known to play an
important role in keeping regions of chromosomes turned off. Sirtuin controls
the enzyme that converts acetate, a source of calories, into acetyl-CoA, a key
component of cellular respiration. In humans, there are seven different
sirtuins, SIRT-1 to SIRT-7. SIRT-1 has been studied by scientist for its
potential effect on human cell lifespan.
Resveratrol promotes normal activity of SIRT-1. Studies have
shown that SIRT-1 activates a critical component of calorie restriction in
mammals and promotes fat mobilization. The most recent study (Nature
2006) demonstrated that obese mice fed red wine extract (resveratrol) were
in better health and lived longer than obese mice that were not fed the red
wine extract. The resveratrol group, were more able to maintain heart health
compared to mice that were not fed resveratrol. SIRT-1 activation also
supports healthy mitochondrial function and supports energy expenditure.
Resveratrol has also been shown to have phytoestrogen activity and may support
optimal estradiol activity. Other studies have documented neuroprotective
benefits associated with resveratrol supplementation.
A comparison test was made to evaluate the activating effect on
human SIRT-1 of Resveravine and pure trans-resveratrol. Only the
trans-resveratrol form of the molecule promotes normal activation of the
mammalian SIRT-1 gene in vitro test. Resveravine was more than eight times more
likely to promote SIRT-1 activity than pure trans-resveratrol, showing
that Resveravine is more efficient than resveratrol in promoting the normal
activity of SIRT-1. Therefore, while the specific mechanisms of SIRT-1 and
resveratrol are still unclear, the studies show that SIRT-1 is essential in
lifespan extension and health improvement, and resveratrol promotes SIRT-1
activity.
Studies in numerous species have demonstrated that reduction of
calories 30 to 50 percent below ad libitium levels of a nutritious
diet can promote a longer lifespan, improve overall health, promote normal
stress resistance and decelerate functional decline. Studies showed that,
SIRT-1 activates a critical component of calorie restriction in mammals, and
promotes fat mobilization in adipocytes by repressing PPAR (test conducted
on mice). Because healthy fat levels have been show to promote a longer murine
lifespan, it is suggested that calorie restriction could be connected to SIRT-1
and life extension in mammals.
As an alternative strategy, new research has focused on the
development of calorie restriction mimetics, compounds that mimic the effect of
calorie restriction by targeting metabolic and stress response pathways
affected by calorie restriction, but without restricting caloric intake.
Resveratrol has been suggested as a potential calorie restriction mimetic.
Supplementing mice with resveratrol significantly increases their
aerobic capacity. By promoting healthy SIRT-1 activity, resveratrol promotes
healthy mitochondrial function and supports energy expenditure, thereby
promoting healthy weight. In vivo test conducted on mice on a
high-calorie diet, resveratrol shifts the physiology of middle-aged mice on a
high-calorie diet towards that of mice on a standard diet and promotes their
overall health.
BioVin® Advanced (French Red Wine Extract with 5% resveratrol):
200 mg
Red wine extract containing oligomeric proanthocyanins (OPCs),
known to be extremely effective in supporting cardiovascular health by
supporting normal blood circulation, strengthening blood vessels, and promoting
normal platelet activity. BioVin Advanced provides
OPCs and additional Resveratrol. The red wine grape contains two main
constituents shown to be of significant antioxidant value: red wine polyphenols
(flavonoids) and trans-resveratrol (mentioned above). Oligomeric
proanthocyanins are flavonoid complexes that act as super potent antioxidants
in the human body. BioVin Advanced combines the antioxidant properties of OPCs
with trans-resveratrol to promote phase 2 metabolizing enzymes, which are
involved in the detoxification of the body’s cells, promoting apoptosis
(programmed cell death) in unhealthy cells, promoting healthy cholesterol
levels, and general free-radical scavenging properties.
VitaBlue® Wild Blueberry Extract (12.5% anthocyanins): 50 mg
Blueberries rank highest among many fruits and vegetables for ORAC
activity and contain 25-30 different types of anthocyanins. Anthocyanin gives
blueberries (and other fruits) their rich blue and red coloring, and is a
powerful flavonoid antioxidant. The mechanism of action surrounding
anthocyanins has been studied at the molecular level, demonstrating effects
such as the promotion of healthy cells and apoptosis (programmed cell death).
Blueberries provide large amounts of chlorogenic acid, which is thought to be
important in promoting cellular health. VitaBlue Wild Blueberry Extract
supports the body’s COX-2 inhibitors and provides powerful antioxidants in much
higher quantities than fresh blueberries, and show to be effective in promoting
cardiovascular health, contributing to normal cell cycle traverse, and
maintaining overall cellular health.